Ovarian cancer germ cell - divastudio.ro

Ovarian cancer germ cell, Proceduri ginecologice laparoscopice în timpul sarcinii

The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, epidemiology and pathological features, based on one-year experience in our hospital. Materials and method.

Înțelesul "teratoma" în dicționarul Engleză Ovarian cancer germ cell Laparoscopic gynecological procedures during pregnancy Several conditions are more frequent in pregnancy: appendicitis, cholecystitis, adnexal torsion, adnexal mass, trauma, breast disease, cervical dysplasia or cancer, bowel obstruction. When a pregnant patient has to undergo surgery, the obstetrician, the general surgeon, or the orthopedist, the neurosurgeon as appropriate, together with the anesthetist and the neonatologist must consult each other, establishing the plan of action and performing accordingly. Among all procedures, abdominal interventions have the most significant impact, either considering laparotomy, or laparoscopy. There are several advantages of laparoscopic surgery during pregnancy: decreased pain, smaller abdominal incisions, smaller scars, fewer incisional hernias, shorter recovery and hospitalization time, early normal bowel function and mobilization. There are also some possible disadvantages, such as injuring the pregnant uterus, decreasing uterine blood flow by increased intraabdominal pressure or even carbon dioxide absorption by mother and fetus.

We analyzed 58 cases registered in the Pathology Department as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types. Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors and 46 cases of malignant tumors 39 cases of primary and 7 cases of secondary tumors.

Proceduri ginecologice laparoscopice în timpul sarcinii

The most frequent histologic type was represented by high-grade serous carcinoma Rare primary ovarian tumors were represented by: adult granulosa cell tumor, clear cell carcinoma, mixed serous-mucinous carcinoma and undifferentiated pleomorphic sarcoma 1. The earliest age of all patients with ovarian tumors was 31 years old for the mixed serous-mucinous carcinoma.

Mean age distribution was 52 years old for benign tumors, 51 years old for borderline and 60 years old for malignant tumors. Primary malignant tumors are the most frequent type of ovarian tumors and their age incidence ranges from the third to the eighth decade. The majority of secondary ovarian tumors are of endometrial origin.

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Keywords ovarian tumors, benign, borderline, malignant Rezumat Obiectiv. Scopul acestui studiu este analiza retrospectivă a spectrului de tumori ovariene, din punct de vedere sta­tis­tic, epidemiologic şi al caracteristicilor histopatologice, re­pre­zen­tând experienţa de un an în spitalul nostru Ma­te­ria­le şi metodă.

Am analizat 58 de cazuri, din De­par­ta­­mentul de Anatomie Patologică, înregistrate ca piese de ooforectomie sau histerectomie diagnosticate cu tumori ovariene, cuprinzând diferite tipuri histologice de tumori ovariene benigne, borderline şi maligne. În funţie de caracterul tumoral, am identificat: trei cazuri de tumori benigne, toate asociate cu un alt tip histologic tu­moral în ovarul contralateral, 12 cazuri de tumori bor­der­line şi 46 de cazuri de tumori maligne dintre care 39 de cazuri de tumori primare şi 7 cazuri reprezentând tumori secundare.

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Vârsta minimă în rândul tuturor pacientelor cu tumori ovariene a fost 31 de ani. Vârsta medie pe categorii a fost 52 de ani pentru tumori benigne, 51 de ani pentru tumori borderline şi 60 de ani pentru tumori maligne.

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Tumorile maligne primare reprezintă cel mai frecvent tip de tumori ovariene, cu o incidenţă de vârstă cuprinsă între decadele a treia şi a opta de viaţă. Majoritatea tumorilor ovariene secundare sunt de origine endometrială.

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The relative frequency­ of ovarian tumor is different for western and Asian countries. Two third of ovarian tumors occur in women of reproductive age group 1.

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Borderline tumors occur at slightly older ages and malignant tumors are more common in women between 45 and 65 years old 2. Ovarian cancer represents the fifth cause of cancer and the fifth cause of death due to cancer in females in the European Union 3.

Proceduri ginecologice laparoscopice în timpul sarcinii

There are three major histologic subtypes of surface epithelial tumors: serous, mucinous and endometrioid. Serous carcinomas are divided in: high-grade serous carcinoma and low-grade serous carcinoma. These tumors are associated with KRAS mutation mainly, and smoking is a risk factor, not associated with serous tumors. Mucinos tumors are composed of gastrointestinal type cell containing intracytoplasmic mucin and therefore, malignant tumors should always be carefully examined for excluding metastatic tumors with similar morphology 2,5.

Endometrioid tumors of the ovary are similar to endometrioid tumors of the endometrium. Other rare epithelial tumors include: clear cell tumors, Brenner tumors, mixed serous-mucinous or mixed epithelial-mesenchymal tumors.

Ovarian cancer germ cell

The group includes: teratomas mature, immature and monodermal or highly specializeddysgerminoma, Yolk-sac tumor, non-gestational chorio-carcinoma, embryonal carcinoma and mixed tumors. In this group, only mature teratomas and monodermal teratoma - benign struma ovarii are benign tumors.

Sex-cord stromal tumors include neoplasms that contain granulosa cells, theca cells, fibloblasts, Sertoli cells and Leydig cells, which are derived from ovarian­ stroma, that is formed from sex cords under the influences of coelomic and mesonephric epithelium.

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This type of tumor has clinical importance because of its potential to elaborate large amounts of estrogens and because it has malignant potential. Pure fibromas are hormonally inactive; Sertoli and Leydig cell tumors are active and have masculinizing or de-fe­mi­nization effects 5,7. Metastases derived from non-gynecological sites are eleven times more puffadas de vierme than those derived from female genital organs, the gastrointestinal tract being the most common origin 7.

Ovarian Cancer

Tumors from the stomach, colon, and breast are the three most common neoplasms ovarian cancer germ cell metastasize to the ovary 8. Materials and method We performed a retrospective analysis of ovarian tumor cases registered at the Pathology Department of the Bucharest Emergency University Hospital for a period of one year. The study included 58 cases of oophorectomy, salpingo-oophorectomy or hysterectomy specimens diagnosed with benign, borderline or malignant tumors of various histologic types.

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  2. Ovarian cancer germ cell germ cell tumor of ovary part 2 papillomavirus vaccination side effects The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, epidemiology and pathological features, based on one-year experience in our hospital.
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We classified them according to their morphologic features, we analyzed the age distribution for each category, the clinical manifestations, regional spread, lymph nodes peritoneal involvement or metastases in available cases; the follow-up was possible in a limited number of cases.

All data was obtained from medical records and from the Statistics Department of University Emergency Hospital in Bucharest. Results and discussions Based on their tumoral behavior, we had Figure 1 : three cases 4. In our study we found a smaller prevalence of benign tumors of only 4. Figure 1. The distribution of ovarian tumors over a period of one year The most frequent histologic type among all ovarian tumors was represented by high-grade serous carcinoma Mucinous carcinoma accounted for Studies of molecular alteration have suggested ovarian cancer germ cell this tumors do actually progress from endometriosis 4, We had one case of poorly differentiated carcinoma of unknown origin.

All the metastasis cases were large excision specimens and were integrated in the clinico-pathological context. The gynecological origin is usually less frequent than the hpv therapy yorum origin, which is the first cause of ovarian metastasis 7,8, Rare primary ovarian tumors were ovarian cancer germ cell by: adult granulosa cell tumor Figure 2clear cell carcinoma, mixed serous-mucinous carcinoma, and undifferentiated pleomorphic sarcoma 1.

Figure 2. Intraoperative Amacroscopic B and microscopic C aspect of a voluminous left ovarian cyst in a patient of 60 years old; after the histopathological analysis the diagnose was adult granulosa cell tumor ovarian cancer germ cell note the micro-follicular pattern The earliest age of a patient with ovarian tumor was 31 years old for the mixed serous-mucinous carcinoma, a younger age than mean age for this type of tumor, but cases of patients within 16 to 79 years had been previously reported 13,

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