Sarcom Ewing extrascheletal sub forma unei mase tumorale la nivelul gâtului - prezentare de caz

Cancer sarcoma ewing

Sarcom Ewing extrascheletal sub forma unei mase tumorale la nivelul gâtului - prezentare de caz

It has been reported a low incidence in the head and neck. Magnetic resonance imaging was useful in preoperative evaluation. The treatment consisted in radical resection, and the histological analysis completed the diagnosis. The postoperative management consisted in a combination of chemotherapy for systemic control and irradiation for local control. A very few cases of cervical tumors were reported.

Sarcomul Ewing

Radical resection followed by radio-chemotherapy has good results in the treatment of this rare tumor. Sarcomul Ewing extrascheletal este o tumoră rară, de origine mezenchimală, similară din punct de ve­de­re histologic cu osteosarcomul Ewing. Este o tumoră rar întâlnită la nivelul capului și gâtului. Autorii pre­zin­tă un caz de sarcom Ewing extrascheletal sub forma unei tumori laterocervicale stângi situate posterior de muș­chiul sternocleidomastoidian.

Examenul RMN a fost util în evaluarea preoperatorie.

Centrul de tratare Sarcom

Tratamentul a constat în excizia ra­di­cală a tumorii laterocervicale, urmată de examen his­to­pa­to­logic. Postoperator s-au efectuat chimioterapie pen­tru controlul sistemic și radioterapie pentru controlul lo­­cal.

simptome cancer limfatic copii hpv treatment for abnormal cells

Sarcomul Ewing ex­­trascheletal este o tumoră rară, cu evoluție agresivă. În cancer sarcoma ewing au fost raportate puține cazuri de sarcoame Ewing ex­trascheletale prezentate sub forma cancer sarcoma ewing tumori la­te­ro­cervicale.

Excizia radicală urmată de radiochimioterapie are cele mai bune rezultate în tratamentul acestor tumori.

cancer sarcoma ewing vaccin hpv homme remboursement

It was first recognized by Tefft et al. According to Chao et al.

In head and neck, EES is usually identified in nasal or oral cavities, sinuses or soft tissues 6. EES is characterized by an aggressive course and high rate of recurrences.

The treatment consists in a combination of surgery, radiotherapy and chemotherapy. Case report A year-old female was admitted in ENT Department with a 2-month history of painless posterior left laterocervical mass with rapid evolution Figure 1.

Sarcoma, A glimpse at a rare cancer

Figure 1. Figure 2. MRI transversal plane The videofibroscopy of rhinopharynx, hypopharynx and larynx was normal. The MRI showed a posterior laterocervical solid mass, with a maximum diameter of 8 cm Figure 2 and Figure 3.

Cauze și factori de risc Cauza exactă a sarcomului lui Ewing nu este clară. Nu este moștenit, dar poate fi legat de schimbări în gene specifice care apar în timpul vieții unei persoane. Când cromozomii 11 și 12 modifică materialul genetic, aceștia activează o creștere a celulelor, care poate duce la dezvoltarea sarcomului Ewing.

Figure 3. MRI coronal plane Figure 4. Intraoperative image after complete removal of the tumor Figure 5.

papillomavirus maladie infectieuse

The patient at 2 months after surgery - local recurrence The patient underwent surgical excision followed by histopathological exam Figure 4. The patient underwent 6 chemotherapy cycles with vincristine, doxorubicin and cyclophosphamide, followed by external radiotherapy. Figure 6. PET-CT scan 2 months after surgery - sagittal view At 10 months after initial diagnosis, the patient presented with incomplete resolution of the tumor Figure 8severe radiomucositis grade 4 WHO and was admitted in the oncology department.

Figure 8. EES in head and neck region must be differentiated from lymphoma, cancer sarcoma ewing, poorly differentiated salivary gland tumors, olfactory neuroblastoma, undifferentiated nasopharyngeal carcinoma and melanoma.

cancer sarcoma ewing

Case particularities The localization of EES in the neck is very rare. Comorbidities - immunosuppression caused by chronic use of prednisolone could be an etiologic factor. Delay of the radiotherapy after surgery 2 months caused tumor recurrence, EES being a very aggressive type of tumor.

Ce este sarcomul Ewing?

Bibliografie 1. Head Neck Pathol.

  1. În funcție de tipul de cancer osos, se utilizează diferite metode de tratament.
  2. Centrul de tratare Sarcom | Anadolu Medical Center

Hum Pathol. Eur J Cancer Clin Oncol. J Laryngol Otol. Windfuhr JP. Primitive neuroectodermal tumor of the head and neck: incidence, diagnosis, and management. Ann Otol Rhinol Laryngol.